In both rodents and humans, scientists have found evidence that spironolactone can reduce people's craving for alcohol.
has been in the medicine cabinet for decades, having first been discovered in the late 1950s. It’s a type of steroid primarily used for its diuretic effect, meaning that it induces the loss of water and sodium through increased urine production. It’s long been used to reduce fluid build-up brought on by conditions like heart failure and kidney disease
, lowering the risk of later serious complications; it’s also used in combination with other drugs to reduce high blood pressure. Over the years, it’s become apparent that spironolactone is useful for other health problems beyond these indications. Because it can block the production of androgen hormones linked to excess oil production, for instance, it’sto treat acne in women . And some research has started to show that the receptors inhibited by spironolactone may also play a role in driving people’s consumption of alcohol.
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