Using acetaminophen, the active ingredient in Tylenol, during pregnancy was not associated with increased risk of autism, ADHD or intellectual disability in children, a new study found.
The study, published in the journal JAMA on Tuesday, analyzed the prenatal and medical records of about 2.5 million children born in Sweden between 1995 and 2019. A statistical model comparing children exposed to acetaminophen during pregnancy with those not exposed found that there was a marginally increased risk of autism, ADHD and intellectual disability in the exposed group.
For example, the study found that parents who have neurodevelopmental disorders — which have strong heritability — are also more likely to use pain medications, like acetaminophen, during pregnancy. This relationship might make it seem like children who are exposed to acetaminophen during pregnancy are more likely to develop neurodevelopmental disorders, when, in fact, their increased risk is due to genetics, according to the study.
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