There is an adverse association between calcium channel blocker (CCB) use and glaucoma, according to a study published online Sept. 7 in JAMA Ophthalmology.
The researchers found that use of CCBs, but not other antihypertensive agents, was associated with increased odds of glaucoma after adjustment for key sociodemographic, medical, anthropometric, and lifestyle factors . CCB use was also associated with thinner macular ganglion cell-inner plexiform layer and macular retinal nerve fiber layer thickness , but not with IOP.
"This cross-sectional study adds further support to an adverse association between CCB use and glaucoma, despite no apparent association with IOP," the authors write."This warrants further investigation to determine whether the associations are causal and to probe potential underlying biological mechanisms.
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