A revolutionary drug has been shown to significantly curb cognitive decline in patients with early Alzheimer’s disease.
Half of the participants were administered the dementia drug while the other half were given a placebo. Lecanemab, a monoclonal antibody that’s injected every two weeks, works by clearing the accumulation of amyloid — toxic plaques in the brain that are believed to cause the debilitating neurological disorder.
After 18 months, the lecanemab group’s amyloid level plummeted by 55.48 centiloids, while their placebo-taking counterparts’ increased by 3.64 centiloids — a significant discrepancy. However, the trial was not without its caveats, as some participants experienced adverse side effects. One in 10 reportedly suffered from swelling in the brain — called amyloid-related imaging abnormalities, known as ARIA — while 1 in 6 experienced brain bleeds, according to CNN.
The patient “needs to be monitored by MRI,” Hardy explained. “This increases the burden and expense of the therapy.”Getty Images/Science Photo Library
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