Blood clotting proteins might cause long COVID brain fog, study says

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Blood clotting proteins might cause long COVID brain fog, study says
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A protein that causes blood clots could be an accurate predictor as to whether someone experiences brain fog months after having COVID.

As scientists try to get a better idea of what causes long COVID symptoms, researchers think blood clotting proteins could be what causes the persistent brain fog many COVID-19 long haulers complain of.

The University of Oxford found the high levels of proteins fibrinogen and D-dimer helped predict whether patients would experience brain fog while battling long COVID. Their study included 1,837 adults hospitalized with COVID-19. The researchers said the presence of the two proteins at the time of hospitalization helped predict the patients' cognitive outcomes six and 12 months after hospitalization.

The Centers for Disease Control and Prevention lists 19 different ailments as common long COVID symptoms. The symptoms can range from prolonged coughs and fevers, symptoms common in primary COVID infections, to neurologic and cardiovascular symptoms.Researchers said their goal is to prevent and reverse the cognitive problems seen in some people after COVID-19 infection.

"Identifying predictors and possible mechanisms is a key step in understanding post-COVID brain fog. This study provides some significant clues," said Oxford professor Paul Harrison.

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