Clonidine can expand or extend the benefits of stimulant ADHD medications for children whose symptoms aren’t fully alleviated by stimulant medication, especially for children with oppositional defiant disorder, Tourette’s syndrome, or tics.
Jain, Rakesh, et al. “Clonidine extended-release tablets for pediatric patients with attention-deficit/hyperactivity disorder.”10.1016/j.jaac.2010.11.005Kollins, Scott, et al. “Clonidine Extended-Release Tablets as Add-on Therapy to Psychostimulants in Children and Adolescents With ADHD.”Hazell, Philip, L., et al.
“A Randomized Controlled Trial of Clonidine Added to Psychostimulant Medication for Hyperactive and Aggressive Children.”10.1097/01.CHI.0000046908.27264.00Barrett, Jessica, et al. “To sleep or not to sleep: a systematic review of the literature of pharmacological treatments of insomnia in children and adolescents with attention-deficit/hyperactivity disorder.”, 23: 640-7. December 2013. doi:Ruiling, Luan, et al.
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