In collaboration with the International Conference on Research in Computational Molecular Biology (RECOMB), Genome Research publishes a collection of 20 computational methods and their applications in genomics including spatial, single-cell, and long-read sequencing.
Cold Spring Harbor Laboratory Oct 13 2024 In collaboration with the International Conference on Research in Computational Molecular Biology , Genome Research publishes a collection of 20 computational methods and their applications in genomics including spatial, single-cell, and long-read sequencing.
In another study, Hong et al. developed SF-Relate, a practical and secure federated algorithm for identifying genetic relatives across distributed genomic datasets. Using novel hashing and bucketing strategies, SF-Relate distinguishes relatives from nonrelatives and securely estimates kinship using encrypted data. This method allows for the exclusion of close relatives that can introduce bias in study results while providing privacy protection.
Another method, DIISCO , characterizes the temporal dynamics of cell–cell interactions in complex biological systems using single-cell RNA sequencing data, elucidating mechanisms underlying normal biological processes and disease progression. This method was demonstrated on simulated and experimental lymphoma–immune interaction data and revealed immune interactions of a cytotoxic T cell subtype that expands with therapy.
Research Cancer Cell Cold Dancing Dendritic Cell DNA Evolution Gene Genetic Genetic Information Genetics Genomic Genomics Laboratory Language Ligand Macrophage Malignant Molecular Biology Oncogene Protein Receptor T-Cell Transcriptomics Tumor
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