Cooler Noses May Be Key to Winter's Spike in Colds

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Cooler Noses May Be Key to Winter's Spike in Colds
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Why colds are more likely in wintertime--it has to do with the nose.

could spread more easily," said senior researcher Dr. Benjamin Bleier, director of Otolaryngology Translational Research at Mass Eye and Ear.

But the nose is capable of fighting this infection. Cells in the front of the nose can detect inhaled germs, and respond by releasing billions of tiny fluid-filled sacs intoThese sacs, called extracellular vesicles , shuttle antibacterial proteins throughout theTo see how this response works in varying conditions, researchers collected samples from the noses of patients and volunteers.

"Combined, these findings provide a mechanistic explanation for the seasonal variation in upper respiratory infections," said lead author Di Huang, a research fellow at Mass Eye and Ear and Northeastern.

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