Paxlovid — the only medication people can take at home to treat an active case of Covid — is now being studied as a potential treatment for those who have remained sick months or even years following infection.
"It is known that Covid can go to multiple sites in the body," she said."The question is, does it set up shop there? And is it quiet enough so that our immune system is not getting rid of it adequately?"
Half of them will get the actual drug, while the others will get a placebo. While Paxlovid is generally given for five days, this study will have participants take it for 15. This is meant, in part, to address the possibility that the drug needs more time to work well. Many patients newly diagnosed with Covid have reported rebound symptoms after their typical five-day treatment course.There is already evidence people who take Paxlovid for Covid are less likely to develop long-lasting symptoms.
Dr. Ziyad Al-Aly, a clinical epidemiologist at Washington University in St. Louis, led the study. The leading long Covid researcher said that while he is eager to see how Paxlovid does in the Stanford study, he suspects that the drug may not be useful after someone has already been suffering for a while.
Others get worse, especially if they become re-infected, said Dr. Monica Verduzco-Gutierrez, the chair of the department of rehabilitation medicine at the Long School of Medicine at UT Health San Antonio. She is not involved with either the Stanford or the VA research.Verduzco-Gutierrez said that studying Paxlovid in people with long Covid"makes sense" because"sometimes viruses hide in certain cells, and it's hard to get to them.""I don't know," she said.
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