An experimental treatment, gantenerumab, failed to help people at high risk of memory loss from Alzheimer’s or those who were in the early phases of the disease, the manufacturer said
Monday. Gantenerumab is part of a class of injected drugs that are designed to remove sticky protein pieces called beta amyloid from the brain. Beta amyloid buildup is a hallmark of Alzheimer’s disease. Most of these drugs have worked as intended to clear the beta amyloid, but many have still failed to demonstrate any real-life benefits to patients; their brain function and memory doesn’t improve significantly, despite treatment.
The results for gantenerumab follow positive results for a different beta amyloid reducing drug, lecanemab. The companies testing that medication, Biogen and Eisai, announced this year that lecanemab had slowed the decline of brain function in Alzheimer’s disease by about 27% compared with a placebo.
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