'The drugs can cause dangerous abnormalities in heart rhythm in coronavirus patients, and should be used only in clinical trials or hospitals where patients can be closely monitored for heart problems, the Food and Drug Administration warned.'
The warning is based on reports from multiple sources that described adverse events, including several types of abnormal heart rhythm, “and in some cases death,” the F.D.A. said.
There is no proven treatment for the coronavirus, and there is no proof that hydroxychloroquine and chloroquine can help coronavirus patients. Those two drugs are approved to treat malaria and the autoimmune diseases lupus and rheumatoid arthritisBut earlier reports from France and China suggesting a benefit led to interest in the drugs, even though the reports lacked the scientific controls needed to determine whether the drugs actually worked. The French study was later discredited.
“I have been very clear of the importance of doing randomized controlled trials to definitively prove whether something is both safe and effective,” he said in an interview.
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