Infection with the first widely circulating version of Omicron protects against the emerging BA.2 subvariant — as does vaccination.
To investigate such worries, Troels Lillebaek, a molecular epidemiologist at the State Serum Institute in Copenhagen, and his colleagues plunged into Denmark’s extensive medical registries. Close to two million Danish residents tested positive for COVID-19 from late November to mid-February, but only 1,739 people had results classed as a reinfection: two positive tests separated by 20–60 days.
The researchers sequenced viral samples from 263 of these people and found that only 47 had contracted BA.2 after an infection with BA.1. By contrast, 140 people had contracted BA.2 after infection with theThe BA.2 subvariant has been proliferating in Denmark since the start of this year, and currently comprises about 88% of all coronavirus cases. But Lillebaek says the wave of BA.1 that preceded BA.
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