How to talk about autism: reconciling genomics and neurodiversity - Nature Medicine

A new study shows that genetic & non-genetic factors contribute to autistic traits, calling for a realignment of the concepts of genomics to incorporate the biosocial complexity of autism News & Views from kristienhens, Luca Chiapperino UAntwerpen unil

Rolland et al. found that rare loss-of-function variants previously associated with autism are also present in the general population and that these variants are associated with a decrease in IQ scores and income among the carriers — what the authors call ‘sub-diagnostic effects’. Of note, the authors offer a complex and multifactorial explanation of the contribution of these LoF variants in the various populations of reference .

However, the authors carefully postulate that there are unknown social–biological processes that make some people with a genetic predisposition to autism resilient to the manifestation of the condition. Therefore, specific social environments might act together with biological predispositions to produce both risk and resilience. Given the sensitivity of genetic findings related to IQ and autism, the authors should be commended for their careful interpretation and presentation of their results.

We have summarized this news so that you can read it quickly. If you are interested in the news, you can read the full text here. Read more:

NatureMedicine /  🏆 451. in US

Singapore Latest News, Singapore Headlines

Similar News:You can also read news stories similar to this one that we have collected from other news sources.

California library using robots to help teach children with autismIt was a surprise first meeting for Luke Sepulveda and his new futuristic robot friend at the Santa Ana Public Library in Southern California.
Read more »

BMI measurement deemed ‘racist’ in new medical report: ‘This is politics, not medicine'In a new report, the American Medical Association (AMA) calls for abolishing the body mass index (BMI) as a means of assessing body fat. Dr. Marc Siegel weighed in with reaction.
Read more »

Penn Medicine stops submitting data to U.S. News ‘best hospital’ rankingsThe move takes effect in 2024, as Penn already submitted data for new rankings that come out this summer.
Read more »

Leveraging the structures of the COVID-19 pandemic response for successful control of Ebola in Uganda - Nature MedicineLeveraging the structures of the COVID-19 pandemic response for successful control of Ebola in Uganda. Correspondence from Hskyobe and colleagues MinofHealthUG
Read more »