An exploration of advancements in fertility treatments and why the burden of treatment so often falls on women.
Illustration of sperm swimming toward an egg.According to Dr. Beim, Celmatix has successfully used AI in their drug discovery efforts. “Our pipeline of drugs is a result of leveraging data to highlight the most promising opportunities,” Dr. Beim explained toThe burden on women
Dr. Beim addresses this issue by pointing out that studying infertility involves extended treatment protocols. "This increases the cost of developing drugs through longer clinical trials and also the timeline to a live birth outcome for individuals experiencing infertility," she noted. Underscoring the intricate relationship between reproductive health, social dynamics, and gender-based violence, a recentsheds light on the prevalence of partner violence among infertile women in low- and middle-income countries.
Consequently, FSH receptors play a vital role in the reproductive system, responding to follicle-stimulating hormone . Manipulating FSHRs can profoundly impact fertility outcomes, making them a critical target for fertility treatments.Celmatix is working to develop the first oral FSHR agonist drug. This drug aims to trigger the FSHRs in a controlled manner and in doing so, mimic the effects of the naturally occurring follicle-stimulating hormone FSH in the body.
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