Looking to gamble, newest U.S. health agency places first research bets

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Looking to gamble, newest U.S. health agency places first research bets
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ARPA-H's director says it aims to be unlike the more cautious NIH

A year ago, when applied biologist Renee Wegrzyn took the helm of the Advanced Research Projects Agency for Health , questions swirled around the brand-new agency, which was created by President Joe Biden to fund daring, cutting-edge biomedical research.

“They have launched some novel and exciting projects” that are “complementary” to the work of NIH, adds Ellen Sigal, CEO of Friends of Cancer Research, a research advocacy group. Several initial recipients are former DARPA awardees; that’s not surprising, says Brad Ringeisen, former director of DARPA’s biotechnology division and now at the University of California, Berkeley. “I think it makes sense to leverage some of those past performers,” he says. In contrast to DARPA research, which is meant to help the military or its soldiers, ARPA-H’s projects aim to improve the health of all Americans.

The agency is also forming what it calls “a hub-and-spoke health innovation network,” dubbed ARPANET-H, to help coordinate efforts such as clinical trials or tests of devices in community health centers or rural hospitals. Staff will be based in three centers: the agency’s Washington, D.C.

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