Women undergoing fertility treatment who smoke marijuana may have more success if they quit, recent research suggests.
Among more than 400 women undergoing treatment with assisted-reproduction technology , the small fraction who reported using cannabis at the time were more than twice as likely to lose a pregnancy than those who had never smoked marijuana, or who had only used it in the past, Dr. Jorge E. Chavarro of Harvard T.H. Chan School of Public Health in Boston and his colleagues found.
Just three studies have looked at how marijuana smoking by both partners affects fertility, the researchers note. Two of them, in couples trying to conceive naturally, found no effect. The third, in couples using ART, found no effect on pregnancy or live births but did find users had lower egg yields and fertilization rates.The new study included 421 women who underwent 730 cycles of ART between 2004 and 2017 at a Boston fertility center. Male partners of 200 of the women also enrolled.
Some animal studies have suggested that activating the endocannabinoid system - naturally occurring signaling molecules that chemically resemble cannabis - at low levels improves testicular function, while higher levels of activation depress it, Chavarro noted.
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