Investigation into possible data manipulation in heart studies, saying a blood thinner had healing effects.
The Journal of Molecular and Cellular Cardiology and the Journal of Biological Chemistry are investigating five papers authored by Temple scientists, the journals told Reuters.a paper by Temple researchers on its website after determining that there was evidence of data manipulation. The retracted paper had originally concluded that the widely-used blood thinner, Xarelto, could have a healing effect on hearts.
His colleague Steven Houser, senior associate dean of research at Temple and former president of the American Heart Association, is listed as an author on five studies supervised by Sabri. Houser was also involved in four additional papers under scrutiny. Several research experts said that Houser, as one of multiple co-authors, cannot be assumed to be involved in potential misconduct. The ultimate responsibility for a study usually lies with the supervising scientist and any researcher who contributed the specific data under scrutiny.The probes highlight concerns over potential fabrication in medical research and the federal funds supporting it.
In some misconduct inquiries, universities have notified scientific journals that an investigation is underway. That has allowed journals to issue an"expression of concern" about specific studies, telling readers that there may be reason to question the results. If there is a finding of data manipulation, the journals would be expected to retract the paper.
The AHA said it had not been notified by the U.S. agency or by Temple about their inquiry, and that it does not view itself as responsible for investigating further. The AHA said it had issued a correction of data on one paper at the authors' request. The paper was the sole study under scrutiny that listed Houser as supervising researcher.
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