Mounjaro: Powerful new obesity drug poised to upend weight loss care

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Mounjaro: Powerful new obesity drug poised to upend weight loss care
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Eli Lily reported that the drug helped people with diabetes who were overweight or had obesity lose up to 16% of their body weight over 17 months in a late-stage trial.

ABC News chief medical correspondent Dr. Alok Patel breaks down all you need to know about Mounjaro and the safety precautions surrounding it.

Having diabetes makes it notoriously difficult to lose weight, said Dr. Nadia Ahmad, Lilly's medical director of obesity clinical development, which means the recent results are especially significant. "We have not seen this degree of weight reduction," she said. Industry analysts predict that tirzepatide could become one of the top-selling drugs ever, with annual sales topping $50 billion. It is expected to outpace Novo Nordisk's Ozempic -- a diabetes drug used so commonly to shed pounds that comedian Jimmy Kimmel joked about it at the Oscars -- and Wegovy, a version of the drug also known as semaglutide approved for weight loss in 2021.

"Psychologically, you don't want to eat," said Barlow. "Now I can eat two bites of a dessert and be satisfied." The obesity medications help overcome a biological mechanism that kicks in when people diet, triggering a coordinated effort by the body to prevent weight loss. Though the drugs appear safe, they can cause side effects, some serious. Most common reactions include diarrhea, nausea, vomiting, constipation and stomach pain. Some users have developed pancreatitis or inflammation of the pancreas, others have had gallbladder problems. Mounjaro's product description warns that it could cause thyroid tumors, including cancer.

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Mounjaro: Powerful new obesity drug poised to upend weight loss careMounjaro: Powerful new obesity drug poised to upend weight loss careEli Lily reported that the drug helped people with diabetes who were overweight or had obesity lose up to 16% of their body weight over 17 months in a late-stage trial.
Read more »

Mounjaro: Powerful new obesity drug poised to upend weight loss careMounjaro: Powerful new obesity drug poised to upend weight loss careEli Lily reported that the drug helped people with diabetes who were overweight or had obesity lose up to 16% of their body weight over 17 months in a late-stage trial.
Read more »

Mounjaro: Powerful new obesity drug poised to upend weight loss careMounjaro: Powerful new obesity drug poised to upend weight loss careEli Lily reported that the drug helped people with diabetes who were overweight or had obesity lose up to 16% of their body weight over 17 months in a late-stage trial.
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