Mystery Solved: Scientists Decode One of the Living World’s Fastest Cell Movements

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Mystery Solved: Scientists Decode One of the Living World’s Fastest Cell Movements
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Researchers have discovered the genes and proteins responsible for the rapid withdrawal of heliozoan arms in response to changes in the environment. This is one of the fastest-known examples of cell motility. Raphidocystis contractilis is a type of eukaryote in the Heliozoa group, found in fresh,

withdraws its axopodia a few milliseconds after encountering an external stimulus. Researchers from Okayama University, Japan report that microtubule dynamics hold the key to this instant arm shortening. Credit: Motonori Ando from Okayama University

To this end, a team of researchers including Professor Motonori Ando, Dr. Risa Ikeda , and Associate Professor Mayuko Hamada , of Okayama University, Japan, explored the mechanism involved in one of the fastest cell movements in the living world. The authors started their investigation by immunolabelling the tubulin protein and observing its movement before and after axopodial contraction. They found that before shortening, tubulins were arranged systematically all along the length of the axopodia, but after axopodial withdrawal, those swiftly accumulated at the cell surface. This led them to believe that during the rapid axopodial withdrawal, the microtubules broke down into tubulin instantly.

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