Researchers have developed a blood test for Alzheimer's disease that could pave the way for better research and less invasive diagnosis of the disease.
Dec. 28, 2022 – Researchers have developed a blood test for Alzheimer’s disease that could pave the way for better research and less invasive diagnosis of the disease. Scientists are particularly hopeful that the new test will facilitate a needed increase in diversity among research study participants.
Alzheimer’s research studies require comprehensive standardized diagnostic techniques, and one aspect of diagnosis can currently only be achieved by brain imaging that is typically only available at high-level medical centers. That makes people with limited access to transportation or who live far away from medical centers less likely to participate in clinical trials that require the imaging.
In the new study, researchers compared existing diagnostic techniques to their newly developed blood test, which detects an important blood biomarker called “brain-derived tau.” The results showed that brain-derived tau levels can reliably indicate Alzheimer’s-specific neurodegeneration. Previously, it had been difficult to differentiate Alzheimer’s-specific biomarkers from those associated with diseases like Parkinson’s and other dementias.
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