Blood clots are one of the body's most important natural defense systems, a mechanism for plugging internal and external gaps to keep us alive.
"The idea of using two components allows selective gelation of the hemostatic system as the concentration is enhanced in the wound, mimicking the end effect of the natural clotting cascade,"The first part of the system is a biocompatible polymer nanoparticle called PEG-PLGA that is engineered to bind to whatever platelets the body can provide while injured. Platelets are drawn to the site of an injury, which in turn carries in these bound nanoparticles.
Crucially, the researchers designed the particles in a form where they wouldn't accumulate in places where they shouldn't by having them only crosslink at a high enough concentration. This system would automatically target the site of the problem and provide some help for the body until more comprehensive medical assistance can be given. All that would be required is an injection that first responders could provide.
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