No Benefit of Colchicine After Stroke, TIA: CHANCE-3

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No Benefit of Colchicine After Stroke, TIA: CHANCE-3
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The anti-inflammatory agent, started within 24 hours of acute ischemic stroke or TIA, did not reduce subsequent stroke or other vascular events at 90 days in the CHANCE-3 trial.

Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit., was not associated with a reduction in subsequent strokes or other vascular events at 90 days in the CHANCE-3 trial.

Low-dose colchicine, which acts as an anti-inflammatory agent, has recently been approved in many countries for patients with established atherosclerotic disease or multiple risk factors for cardiovascular disease to reduce the risk for future cardiovascular events. This follows benefits seen in those populations in the

"Clinical trials with longer treatment times are needed to further assess the effects of colchicine after cerebrovascular events, but it may be that ischemic cerebrovascular disease and, co-chair of the WSC session at which it was presented, Ashkan Shoamanesh, MD, associate professor of medicine at McMaster University in Canada, said CHANCE-3 was a well-designed large phase 3 randomized trial and the first such trial to test colchicine for...

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