No Sweat: Superhydrophobic Biosensor Reads Your Body’s Invisible Signals

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No Sweat: Superhydrophobic Biosensor Reads Your Body’s Invisible Signals
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A new superhydrophobic biosensor enables the monitoring of 'insensible' sweat (vaporized water loss from the skin), which was previously hard to measure. This sensor can be integrated into wearable tech for continuous tracking, aiding in assessing body thermoregulation, skin health, disease conditio

A biosensor developed by Huanyu “Larry” Cheng, the James L. Henderson, Jr. Memorial Associate Professor of Engineering Science and Mechanics, features superhydrophobic material that measures sweat vapor without absorbing water. Credit: Provided by Larry Cheng/Penn State

Sweat contains biomarkers that help doctors make health diagnoses. Wearable sensors can be used to monitor a person’s perspiration rate and provide information about the skin, nervous system activity, and underlying health conditions. But not all sweat is created equal, and some cannot be measured with current sensors. A newly developed superhydrophobic biosensor could be used as a diagnostic tool to detect such types of sweat.

“Monitoring insensible sweat is of high interest for evaluating skin health and disease conditions, such asand wound healing, as well as underlying health statuses, such as pain or anxiety,” Cheng said. “Skin-interfaced devices that detect sweat rate and loss are currently limited to working with sensible sweat and are not suitable for insensible sweat in a vapor state.”

Cheng developed a prototype of a superhydrophobic sweat sensor to measure vapor from insensible perspiration. The material — a superabsorbent hydrogel composite on a porous substrate sandwiched between two superhydrophobic textile layers — allows the permeation of sweat vapor while preventing the sensor from being affected by the external water droplets of sensible perspiration.

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