Pfizer’s hemophilia B treatment meets primary endpoint in Phase 3 study

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Pfizer’s hemophilia B treatment meets primary endpoint in Phase 3 study
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Pfizer Inc. said Thursday that a Phase 3 study of fidanacogene elaparvovec for the treatment of hemophilia B in adult males met its primary endpoint of...

Pfizer Inc. said Thursday that a Phase 3 study of fidanacogene elaparvovec for the treatment of hemophilia B in adult males met its primary endpoint of superiority in the annualized bleeding rate . The drug maker PFE said key secondary endpoints demonstrated a 78% reduction in treated ABR and a 92% reduction in annualized infusion rate. Pfizer said fidanacogene was also “well tolerated,” and in line with Phase 1/2 results.

The drug maker PFE said key secondary endpoints demonstrated a 78% reduction in treated ABR and a 92% reduction in annualized infusion rate. Pfizer said fidanacogene was also “well tolerated,” and in line with Phase 1/2 results. There were 14 serious adverse events reported in seven, or 16%, of patients, with two assessed as related to treatment, and no deaths.

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