Researchers develop first printed 3D heart in major scientific breakthrough.
Given the number of patients suffering from CHF each year, and its high healthcare costs, the study’s researchers were determined to “develop new approaches to regenerate the infarcted heart.”
The 3D heart was created from human cells obtained through biopsies. These tissue samples were experimentally reprogrammed to become “pluripotent” or de-identified stem cells. The stem cells were then exposed to chemicals or “bioinks” that helped to retrain them to become either heart or blood vessel cells.
“The biocompatibility of engineered materials [was] crucial to eliminate the risks of implant rejection, which jeopardizes the success of such treatments,” said Dr. Dvir. Transplant rejection, which occurs when the recipient’s immune system targets transplanted tissue, is a common problem in heart transplant patients. It typically occurs within one year of heart transplantation,Although the 3D human heart represents a promising step towards transplant engineering, further research is needed.
Navjot Kaur Sobti is an internal medicine resident physician at Dartmouth-Hitchcock-Medical Center/Dartmouth School of Medicine and a member of the ABC News Medical Unit.
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