Researchers discovered a new class of iron-targeting compounds that hamper the proliferation of cultured malignant cells in a laboratory setting.
Researchers at the University of Arizona Cancer Center discovered a new class of iron-targeting compounds that hamper the proliferation of cultured malignant cells in a laboratory setting.
The team has been working with Tech Launch Arizona, the university's commercialization arm, with the goal of licensing the technology to a company that will move it into the marketplace. A patent application is pending. Tomat said the research team's challenge was capturing iron within malignant cells yet keeping it available to the rest of the body. To do so, they targeted intracellular iron with compounds that are activated only after cellular uptake.
The research was inspired by a"common reagent," a compound that is employed in laboratories worldwide to assess the ability of drug candidates to inhibit the proliferation of cultured mammalian cells.
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