Mini brains grown in a lab from stem cells spontaneously developed rudimentary eye structures, scientists reported in a fascinating 2021 paper.
spontaneously developed rudimentary eye structures, scientists reported in a fascinating 2021 paper.
"These organoids can help to study brain-eye interactions during embryo development, model congenital retinal disorders, and generate patient-specific retinal cell types for personalized drug testing and transplantation therapies." . Such 'mini brains' are used for research purposes where using actual living brains would be impossible, or at the very least, ethically tricky - testing drug responses, for example, or observing cell development under certain adverse conditions.In previous research, other scientists had used embryonic stem cells to grow optic cups, the structures that develop intoduring embryonic development.
Previous work in the development of organoids showed evidence of retinal cells, but these did not develop optic structures, so the team changed their protocols.
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