Australian scientists have created the most detailed map ever of the communication links between the hippocampus, the brain's memory control center, and the rest of the brain, potentially revolutionizing our understanding of human memory. “We were surprised to find fewer connections between the h
A highly detailed ‘wiring diagram’ of the human brain reveals the multitude of various connections. Credit: Human Connectome Project
Located within the brain, the hippocampus is a complex structure that resembles a seahorse. It is essential for the brain and plays a crucial role in memory formation as well as the transfer of memories from short-term to long-term storage. In addition to these functions, the hippocampus also plays a role in navigation, the ability to imagine future or fictitious experiences, the creation of mental imagery, and even in visual perception and decision-making.
They processed the existing HCP data using tailored techniques that they developed. This allowed them to follow the connections from all corners of the brain to their termination points in the hippocampus – something that had never been accomplished before in the human brain.“What we’ve done is take a much more detailed look at the white matter pathways, which are essentially the highways of communication between different areas of the brain,” said Dr Dalton.
Technical limitations inherent to previous MRI investigations of the human hippocampus meant it was only possible to visualize its connections in very broad terms. “But we have now developed a tailored method that allows us to confirm where within the hippocampus different cortical areas are connecting. And that hasn’t been done before in a living human brain,” said Dr. Dalton.
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