Obstetrics researcher Marlena Fejzo knows a thing or two about nausea and vomiting in pregnancy.
As she endured sickening nausea in her second pregnancy, unable to keep any food down and feeling too weak to stand,Fejzo leads a team of researchers that now, after decades of research, has singled out one hormone which acts on the brain to cause vomiting as the likely cause of morning sickness – and added a stack of new evidence to back up their claims.
"Our findings place GDF15 at the mechanistic heart of [nausea and vomiting in pregnancy] and HG and clearly point the way to strategies for its treatment and prevention," the researchersNews that scientists might have landed on the cause of hyperemesis should bring some relief to those who are pregnant, even if no new treatments have been developed from the discovery just yet.
Returning to the previously identified genetic variants linked to HG, Fejzo and her team found women with these variants had markedly lower levels of the GDF15 hormone circulating in their blood when they weren't pregnant.
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