Specific Risk Factors Predict Quality-of-Life Outcomes in MS

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Specific Risk Factors Predict Quality-of-Life Outcomes in MS
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Specific factors place newly diagnosed patients with MS at risk for worse mental and physical HRQoL over the course of their disease, new research suggests. multiplesclerosis

Researchers analyzed data on 4888 participants who enrolled in the North American Research Committee on Multiple Sclerosis registry within 3 years of their MS diagnosis. The self-report registry was established in 1996 to collect demographic and clinical information from patients with MS.

17.1% experienced an early decline in physical HRQoL within the first 8 years after diagnosis and then an increase to moderate/normal HRQoL thereafter; and For participants with the lowest HRQoL, the average age at MS diagnosis was 46 years, vs an average age of 38 years for those who reported the highest HRQoL.

"Sometimes people might actually have other physical impairments because they are older, but they might have more life experience and know that life sometimes throws us curve balls and might be better equipped with stable jobs, housing, relationships, and family life ― and might be able to better cope with the diagnosis," O'Mahony said.

"While interesting, it is not clear that these findings will impact clinical treatment or management of MS since they do not really provide new data and the factors identified here are largely not readily modifiable," said Bhargava, who was not involved with the research.

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