‘Transformative’: FDA approves first drug for postpartum depression

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‘Transformative’: FDA approves first drug for postpartum depression
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Brexanolone is not a pill. The drug is delivered intravenously over the course of a 60-hour infusion, meaning it must be administered in a medically supervised setting, such as a skilled facility or a hospital, rather than at patients’ homes.

that uses the active ingredients in the club drug ketamine, as a treatment for severe depression.

Brenley, left, and Hadley Hathaway. Their mother, Stephanie Hathaway, participated in a trial for the first-ever drug developed specifically to treat postpartum depression, brexanolone.She participated in a brexanolone trial, and her response was striking. Between hours 12 and 18 of the 60-hour infusion, she noticed her despair had waned.

"It’s all fantasy until we actually have the baby. And then you do feel guilty, because we all want to be Super Mom.” In the past decade, experts say, there has been more awareness about postpartum depression and more efforts among obstetricians and pediatricians to screen mothers for it.But having a drug specifically aimed at treating postpartum depression will be one of the most significant steps toward removing any stigma still associated with the condition, said Dr. Kimberly Yonkers, professor of psychiatry, epidemiology and obstetrics, gynecology and reproductive sciences at the Yale School of Medicine.

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