The cells produce a neurotransmitter, called gamma-aminobutyric acid, to block overactive impulses between nerve cells in the brain, the press release says.
SAN DIEGO — UC San Diego Health is one of the first facilities in the nation using a new, experimental therapy to relieve epilepsy patients of their seizures, according to a press release from the medical center.
Dr. Sharona Ben-Haim conducted the complex procedure, injecting multiple interneurons into precise points mapped out on the patient's brain. “This experimental therapy offers us the potential to essentially restore the balance in the brain to be able to calm and ideally stop the seizures, while retaining the normal function of that part of the brain," she says."Currently, we do not have a therapy that allows us to do that, so this is really exciting.”Neurona Therapeutics is sponsoring the clinical trial, and it is looking for 40 participants from around the country to enroll in the trial.
According to the Centers for Disease Control and Prevention, epilepsy is the fourth most common neurological disorder in the country, behind migraines, strokes and Alzheimer's disease. Nearly 3.5 million Americans have epilepsy, and roughly a third of those people don't see positive results from anti-seizure medications, the press release says.
Patients in the clinical trial will be monitored regularly for two years after the surgery, so researchers can observe the effects of the implanted stem cells. According to the press release, preliminary data reported in June shows seizure frequency dropped by 90% for the first two patients 19 months after their treatments.
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