Why does mental effort lead to a more resilient brain that can withstand dementia and decline? We are now discovering the mechanisms behind this cognitive reserve, opening up new ways to boost it
My failure to recognise the extent of her cognitive decline was born partly of denial, but also because she was doubtless compensating for her galloping brain damage, taking cerebral detours around the potholes dug by her condition. After all, she had done this before. Following a stroke four years previously, she had lost the ability to read; after much hard work, she learned the skill again.
So how come this ability to adapt, which seemed to sustain her after her stroke, was unable to withstand the pathology of dementia? This also made me think about my ownWe have known for almost three decades that some peoples’ brains can function normally even when, due to an enigmatic capacity called cognitive reserve. Yet despite growing evidence of its importance, it has been challenging to pin down how this quality operates in the brain.
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