'Maybe, in 10 years, there will be organ printers in the finest hospitals around the world, and these procedures will be conducted routinely,' said Tal Dvir of Tel Aviv University, where the organ was made.
Israeli researchers have created what they say is the world’s first 3D-printed heart, made using cells and biological material from a human patient.
"This heart is made from human cells and patient-specific biological materials,” Dvir said. “In our process, these materials serve as the bio-inks—substances made of sugars and proteins that can be used for 3D printing of complex tissue models. People have managed to 3D-print the structure of a heart in the past, but not with cells or with blood vessels. Our results demonstrate the potential of our approach for engineering personalized tissue and organ replacement in the future.
To create the heart, the researchers used a bio-ink gel made out of fatty tissue extracted from a patient. In total, the printing process took about three hours. The team say that using material extracted from the patient is very important when creating organs for transplant. "We need to develop the printed heart further," Dvir said."The cells need to form a pumping ability; they can currently contract, but we need them to work together. Our hope is that we will succeed and prove our method's efficacy and usefulness. Maybe, in 10 years, there will be organ printers in the finest hospitals around the world, and these procedures will be conducted routinely.
“3D-printing a blood vessel is extremely challenging, as artificial blood vessels tend to burst over time. The current 3D-printed human hearts are excellent for drug testing, but many issues still need to be addressed before we can do a human transplant, for example, the printed heart will need to have long-term functionality without any problems," Radacsi said.
“I am very excited to see how we are getting closer to 3D-printing humans, as can be seen in the TV show, Westworld,” Radacsi said. “I think the 20th century was the century for physics, while the 21st century will be the century of bioengineering.”
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