Scientists are closing in on a way to help young boys undergoing cancer treatment preserve their future fertility — and the proof is the first monkey born from the experimental technology.
WASHINGTON —
"Fertility issues for kids with cancer were ignored" for years, said University of Pittsburgh reproductive scientist Kyle Orwig."Many of us dream of growing up and having our own families. We hope our research will help these young patients to do that." Boys are born with stem cells inside little tubes in the testes, cells that start producing sperm after puberty's testosterone jolt. Orwig's goal: Keep sperm-producing stem cells safe from cancer treatment by freezing small pieces of testicular tissue, and using them to restore fertility later in life.Orwig's team froze tissue from young male monkeys, and then sterilized them.
The new research shows"immature testicular tissue may become an option" to preserve boys' fertility, Nina Neuhaus and Stefan Schlatt of the Center of Reproductive Medicine and Andrology in Muenster, Germany, wrote in an accompanying editorial.
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