RNA interference (RNAi) therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and cancer.
University of MarylandAug 20 2024 RNA interference therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and cancer. These therapeutics can target and silence disease-causing genes with high precision, minimizing off-target effects and improving treatment outcomes.
Antony Jose, study's senior author, associate professor of cell biology and molecular genetics at UMD These findings highlight the need to consider drug resistance when developing RNAi-based treatments, according to Jose. Just as bacteria can become resistant to antibiotics, we may also become resistant to silencing over time.
"Losing certain proteins can make it harder to silence some genes but not others," Jose said. "Knowing how these proteins work together to affect genes can make a difference when designing drugs tailored to an individual."
RNA Cancer Gene Gene Expression Gene Silencing Genes Genetic Research RNA Interference Rnai Sirna Therapeutics
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